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+1-888.733.6849
+1-617.299.7367 (Int’l)
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| Reactivity | Human Mouse |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Calculated MW | 36kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human APOE |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | APOE;AD2;LDLCQ5;LPG;MGC1571; |
Western blot analysis of extracts of various cell lines, using APOE antibody.
Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using ApoE antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using ApoE antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded human lung using ApoE antibody at dilution of 1:100 (x40 lens).
The apolipoprotein E(APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of apoE isoforms but do not provide mechanistic insight
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