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+1-888.733.6849
+1-617.299.7367 (Int’l)
+1-888.733.6849
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| Reactivity | Human Mouse |
| Tested applications | WB |
| Recommended Dilution | WB 1:500 - 1:1000 |
| Calculated MW | 36kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human CEBPB |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | LAP; CRP2; TCF5; IL6DBP; NF-IL6; C/EBP-beta; |
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
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