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sales@neoscientific.com
+1-888.733.6849
+1-617.299.7367 (Int’l)
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| Reactivity | Human |
| Tested applications | WB IF FC |
| Recommended Dilution | WB 1:500 - 1:1000 IF 1:20 - 1:50 FC 1:20 - 1:50 |
| Calculated MW | 168kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human Gli2 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | AW546128; Gli2; |
GLI2, also named as THP, belongs to the GLI C2H2-type zinc-finger protein family. GLI2 play a role during embryogenesis. It binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1. It is implicated in the transduction of SHH signal. Mutation of GLI2 will cause of holoprosencephaly type 9 (HPE9).
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