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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC IF FC |
| Recommended Dilution | WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:20 - 1:50 FC 1:20 - 1:100 |
| Calculated MW | 51kDa |
| Observed MW | Refer to Figures |
| Immunogen | Recombinant protein of human KRT7 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | KRT7;CK7;K2C7;K7;MGC129731;MGC3625;SCL ;Cytokeratin 7 |
Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments (1,2). Keratin isoforms demonstrate tissue- and differentiation-specific profiles that make them useful as biomarkers (1). Mutations in keratin genes are associated with skin disorders, liver and pancreatic diseases, and inflammatory intestinal diseases (3-6).Keratin 7 and Keratin 19 are present in hepatic and pancreatic progenitor/stem cells (7,8).
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