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| Reactivity | Human |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:2000 |
| Calculated MW | 85kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic peptide of human PLOD3 |
| Storage Buffer | Store at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | f |
| Synonym | LH3; |
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity.
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