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| Reactivity | Human Mouse |
| Tested applications | WB |
| Recommended Dilution | WB 1:200 - 1:1000 |
| Calculated MW | 30kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human RCHY1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | ZCHY; ARNIP; CHIMP; PIRH2; RNF199; ZNF363; PRO1996; |
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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