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| Reactivity | Human Mouse Rat |
| Tested applications | WB |
| Recommended Dilution | WB 1:1000 - 1:3000 |
| Calculated MW | 81kDa |
| Observed MW | Refer to Figures |
| Immunogen | A synthetic peptide of human VCAM1 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Synonym | VCAM1 ; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106 |
Vascular cell adhesion protein 1 (VCAM1) is important in cell-cell recognition. It has been reported to function in leukocyte-endothelial cell adhesion, interact with the beta-1 integrin VLA4 on leukocytes, and mediate both adhesion and signal transduction. There are two isoforms; Isoform 1, a single-pass type I membrane protein, and isoform 2, a lipid-anchor (GPI-anchor). VCAM1 is expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. It is also expressed in the bone marrow (1).
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